Genetic complexity in hypertrophic cardiomyopathy revealed by high-throughput sequencing

Luis R Lopes; Anna Zekavati; Petros Syrris; Mike Hubank; Claudia Giambartolomei; Chrysoula Dalageorgou; Sharon Jenkins; William McKenna; Uk10k Consortium Consortium; Vincent Plagnol; Perry M Elliott

doi:10.1136/jmedgenet-2012-101270

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Genotype-phenotype correlations

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Genetic complexity in hypertrophic cardiomyopathy revealed by high-throughput sequencing

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Feb 2013	497	296	233
Mar 2013	889	389	233
Apr 2013	631	196	138
May 2013	309	178	82
Jun 2013	252	154	69
Jul 2013	263	155	68
Aug 2013	141	62	59
Sep 2013	76	66	72
Oct 2013	98	51	56
Nov 2013	63	70	56
Dec 2013	47	49	48
Jan 2014	58	62	42
Feb 2014	38	70	34
Mar 2014	62	75	53
Apr 2014	45	48	51
May 2014	48	64	39
Jun 2014	42	32	27
Jul 2014	22	56	34
Aug 2014	58	80	35
Sep 2014	25	51	28
Oct 2014	37	68	52
Nov 2014	27	39	26
Dec 2014	35	37	33
Jan 2015	20	45	35
Feb 2015	27	48	32
Mar 2015	37	70	31
Apr 2015	39	45	24
May 2015	42	53	23
Jun 2015	20	37	22
Jul 2015	37	35	23
Aug 2015	35	40	27
Sep 2015	61	60	36
Oct 2015	17	23	14
Nov 2015	60	37	29
Dec 2015	49	56	67
Jan 2016	51	50	39
Feb 2016	47	47	29
Mar 2016	29	29	39
Apr 2016	20	32	29
May 2016	35	35	28
Jun 2016	44	60	43
Jul 2016	69	52	29
Aug 2016	52	56	27
Sep 2016	47	53	39
Oct 2016	66	53	36
Nov 2016	55	68	47
Dec 2016	60	58	33
Jan 2017	48	155	23
Feb 2017	32	47	35
Mar 2017	4	51	60
Apr 2017	4	57	24
May 2017	10	79	33
Jun 2017	17	105	25
Jul 2017	77	68	27
Aug 2017	78	62	26
Sep 2017	72	56	41
Oct 2017	74	63	39
Nov 2017	72	64	26
Dec 2017	79	55	35
Jan 2018	71	67	108
Feb 2018	58	36	163
Mar 2018	88	66	36
Apr 2018	107	53	23
May 2018	68	56	22
Jun 2018	51	49	23
Jul 2018	80	68	31
Aug 2018	87	83	31
Sep 2018	69	63	32
Oct 2018	68	54	24
Nov 2018	86	77	28
Dec 2018	74	66	27
Jan 2019	76	55	28
Feb 2019	69	60	18
Mar 2019	61	45	16
Apr 2019	64	52	21
May 2019	81	71	42
Jun 2019	75	70	46
Jul 2019	59	52	40
Aug 2019	61	61	22
Sep 2019	58	52	27
Oct 2019	64	60	21
Nov 2019	72	62	25
Dec 2019	60	54	17
Jan 2020	69	63	9
Feb 2020	65	55	20
Mar 2020	74	60	28
Apr 2020	55	49	61
May 2020	56	41	64
Jun 2020	49	43	35
Jul 2020	49	47	21
Aug 2020	62	60	44
Sep 2020	52	38	13
Oct 2020	88	55	26
Nov 2020	95	69	39
Dec 2020	66	58	32
Jan 2021	92	80	38
Feb 2021	60	55	37
Mar 2021	72	60	26
Apr 2021	74	64	26
May 2021	67	66	22
Jun 2021	45	45	20
Jul 2021	55	55	32
Aug 2021	53	52	26
Sep 2021	109	109	53
Oct 2021	143	121	66
Nov 2021	95	82	47
Dec 2021	70	63	21
Jan 2022	93	75	36
Feb 2022	61	55	30
Mar 2022	127	137	52
Apr 2022	57	60	20
May 2022	88	96	47
Jun 2022	73	73	31
Jul 2022	58	64	33
Aug 2022	86	83	26
Sep 2022	114	100	30
Oct 2022	75	68	21
Nov 2022	83	77	25
Dec 2022	71	65	25
Jan 2023	86	83	28
Feb 2023	95	90	21
Mar 2023	103	92	32
Apr 2023	55	44	30
May 2023	66	54	27
Jun 2023	58	56	26
Jul 2023	104	95	30
Aug 2023	103	88	61
Sep 2023	136	132	53
Oct 2023	293	280	35
Nov 2023	384	380	20
Dec 2023	185	179	45
Jan 2024	93	93	72
Feb 2024	101	100	35
Mar 2024	167	161	150
Total	11786	10154	5461

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